Micro and nanoscale fluid mechanics transport in microfluidic devices pdf
Micro- and Nanoscale Fluid Mechanics: TransportBrian J. He joined the school in August Previous to that, he was a Senior Member of the Technical Staff in the Microfluidics Department at Sandia National Laboratories in Livermore, California, where he worked from to on microfluidic systems, with applications primarily to counterbioterrorism. He teaches both macroscale and microscale fluid mechanics, and received the Mr and Mrs Robert F. Would you like to tell us about a lower price?
Hydraulic capacitance (compliance) in microfluidic hydraulic circuits
Kirby B.J. Micro - and Nanoscale Fluid Mechanics: Transport in Microfluidic Devices
The isolation and capture of rare cells is a problem uniquely suited to microfluidic devices, in which geometries on the cellular length scale can be engineered and a wide range of chemical functionalizations can be implemented. The performance of such devices is primarily affected by the chemical interaction between the cell and the capture surface and the mechanics of cell— surface collision and adhesion. As rare cell capture technology has been summarized elsewhere [ 1 ], this article focuses on the fundamental adhesion and transport mechanisms in rare cell capture microdevices, and explores modern device design strategies in a transport context. The biorheology and engineering parameters of cell adhesion are defined; adhesion models and reaction kinetics briefly reviewed. Transport at the microscale, including diffusion and steric interactions that result in cell motion across streamlines, is discussed. The review concludes by discussing design strategies with a focus on leveraging the underlying transport phenomena to maximize device performance. Capture of rare cells from complex samples is a long-standing goal of increasing importance.
Brian J. Kirby Publications Textbooks. Barbati AC , Kirby BJ , "Surface conductivity in electrokinetic systems with porous and charged interfaces: Analytical approximations and numerical results", submitted, Bono MS , Ahner BA, Kirby BJ , "Detection of algal lipid accumulation due to nitrogen limitation via dielectric spectroscopy of Chlamydomonas reinhardtii suspensions in a coaxial transmission line sample cell", Bioresource Technology , Volume , pp. Hawkins BG , Kirby BJ "Electrothermal flow effects in insulating electrodeless dielectrophoresis systems," Electrophoresis , , Zahn, Artech Press, Kondapalli S , Kirby BJ "Refolding of beta-galactosidase: Microfluidic device for reagent metering and mixing and quantification of refolding yield," Microfluidics and Nanofluidics 7 2 ,
Cambridge University Press. - Micro- and Nanoscale Fluid Mechanics: Transport in Microfluidic Devices. Brian J. Kirby. Frontmatter.
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